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Is Retinol Cream Good for Neck Lines?

Is Retinol Cream Good for Neck Lines?

by Riversol Skincare

Reviewed by Dr. Jason Rivers, MD, FRCPC (August 2026)

Summary

Yes, retinol cream is good for neck lines, boosting collagen and cell turnover to visibly smooth crepey texture and wrinkles without irritation.

Why Neck Skin Ages Faster Than Your Face

Is retinol cream good for neck lines? The short answer is yes, and dermatologists have been recommending it for this purpose for decades. But the neck presents a unique challenge: its skin is thinner, produces less oil, and is rarely protected with the same diligence as facial skin.

The outermost protective layer of skin (clinically known as the stratum corneum) is measurably thinner on the neck than on the cheeks or forehead. This means the lipid barrier, which keeps moisture in and irritants out, is more easily disrupted. As of 2026, photoaging (UV-induced oxidative stress that breaks down collagen and elastin over time) is recognised as the leading driver of premature neck wrinkles, compounding the natural loss of collagen that begins in our thirties.

According to the American Academy of Dermatology, sagging and wrinkling of neck skin is among the most common cosmetic concerns raised in clinical consultations, and topical retinoids remain a first-line recommendation for non-invasive treatment.

woman examining neck skin in mirror showing visible neck lines and wrinkles
Neck skin ages differently from facial skin due to its thinner barrier and less frequent sun protection.

How Retinol Works on Neck Lines

Retinol is a vitamin A derivative that works by accelerating the natural process of skin cell renewal (clinically known as epidermal cell turnover) and stimulating collagen synthesis in the deeper layers of the skin. Both mechanisms directly address the structural causes of neck lines and crepey texture.

What Retinol Actually Does at the Skin Level

  • Collagen stimulation: Retinol activates fibroblasts, the cells responsible for producing collagen and elastin, helping to restore structural support to thinning neck skin.
  • Cell turnover: By accelerating the shedding and replacement of surface skin cells, retinol reduces the visibility of fine lines caused by uneven texture.
  • Melanogenesis regulation: Retinol helps reduce the appearance of dark spots and uneven pigmentation that commonly accompany neck aging.

A published clinical study cited in PubMed (NCBI, 2024) demonstrated that a retinal formulation was safe, well-tolerated, and effective in improving the appearance of fine lines after consistent use, confirming what dermatologists have observed in practice for years. Separately, a study published in the Journal of the American Academy of Dermatology found that a retinol-containing daily moisturizer produced measurable skin benefits including improved texture and reduced signs of aging with regular application.

The Problem with Retinol on Sensitive Neck Skin

Here is where most people run into trouble. Because the neck's stratum corneum is thinner and the lipid barrier is more fragile, retinol can trigger significant irritation in this area, even in people whose facial skin tolerates it well. Redness, stinging, peeling, and increased transepidermal water loss (TEWL) are common complaints.

In clinical practice, patients with reactive skin or rosacea-prone skin frequently abandon retinol entirely after one or two uncomfortable experiences. This is a real loss, because retinol remains one of the most evidence-backed ingredients for visible anti-aging results. The challenge is not whether retinol works; the challenge is formulating it so that sensitive skin can actually tolerate it.

PRO TIP: If your neck becomes red or flaky after applying retinol, do not give up on it entirely. The problem is usually the concentration or the absence of a calming co-ingredient, not retinol itself. Start with a lower concentration and look for formulations that include an anti-inflammatory ingredient alongside the retinol.

Retinol Plus Beta-T: The Sensitive Skin Difference

Best Retinol Neck Cream for Sensitive and Reactive Skin: Riversol Retinol Neck Cream

Clinically formulated for sensitive, rosacea-prone, and reactive neck skin, the Retinol Neck Cream pairs retinol 0.10% with Hinokitiol (Beta-Thujaplicin, or Beta-T), an anti-inflammatory compound extracted from the Western Red Cedar tree native to British Columbia. Beta-T is widely regarded among dermatologists as a calming agent that helps reduce erythema (skin redness) and suppress the inflammatory cascade that typically causes retinol-induced burning and stinging. This combination is what makes retinol accessible to skin types that would normally react badly to it.

Feature Standard Drugstore Retinol Cream Riversol Retinol Neck Cream
Key Ingredient Retinol (often 0.3% or higher) Retinol 0.10% with Hinokitiol (Beta-T)
Formula Texture Standard lotion or cream, no targeted buffer Cream with anti-inflammatory and barrier-support co-actives
Skin Sensation Can cause stinging, peeling, redness on neck Formulated to minimise irritation on reactive skin
Key Co-Active Typically none targeted at inflammation Niacinamide, Hyaluronic Acid, Tetrapeptide-21, Stabilized Vitamin C

The Retinol Neck Cream is best suited for anyone with reactive or rosacea-prone neck skin who has previously avoided retinol due to irritation.

Beyond Beta-T and retinol, the formula also contains Niacinamide (which supports the skin barrier and reduces erythema), Hyaluronic Acid (which counteracts TEWL and keeps the neck hydrated during cell turnover), Stabilized Vitamin C in the form of Aminopropyl Ascorbyl Phosphate (which supports collagen synthesis and helps with uneven tone), and Tetrapeptide-21 and Acetyl Dipeptide-1 Cetyl Ester (which address sagging and firmness). It is developed by Dr. Jason Rivers, MD, FRCPC, a board-certified dermatologist with decades of clinical experience treating sensitive and rosacea-prone skin, and it is trusted by over 1,000,000 customers across Canada and the United States.

For sensitive skin types seeking visible improvement in neck lines without the burning that typically accompanies retinol, the Retinol Neck Cream is formulated specifically to deliver retinol's anti-aging benefits while keeping reactive neck skin calm and comfortable.

Retinol Neck Cream

Interested in trying Retinol Neck Cream?

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How to Use Retinol Cream on Your Neck

Proper application technique matters as much as the formula itself. The neck is often neglected in skincare routines, which means it may be more reactive when you first introduce retinol.

A Simple, Consistent Approach

  1. Cleanse gently: Use a mild, non-stripping cleanser. The Hydrating Cream Cleanser is formulated to clean without compromising the skin's lipid barrier.
  2. Apply retinol at night: Use a pea-sized amount of retinol neck cream to the neck and chest area. Apply in upward strokes.
  3. Start with two to three nights per week: Allow your skin to build tolerance before moving to nightly use.
  4. Moisturise if needed: If dryness occurs, follow with the Daily Moisturizing Cream to support barrier recovery.
  5. Use SPF every morning: Retinol increases photosensitivity. Apply SPF 30 or higher daily. The Daily Glow Mineral Sunscreen SPF 50+ is a gentle mineral option suitable for reactive skin.

As of 2025, the dermatological literature increasingly emphasises consistent low-concentration retinol use over aggressive high-concentration approaches, particularly for neck and chest skin where barrier function is naturally more limited.

woman applying retinol neck cream in upward strokes as part of a nighttime skincare routine
Apply retinol neck cream in upward strokes two to three nights per week when first starting out.
PRO TIP: Do not layer retinol with glycolic acid or other exfoliating acids on the same evening. These combinations significantly increase the risk of irritation on neck skin. Use them on alternating nights instead.

Frequently Asked Questions

Which Retinol Is Best for Neck Lines?

For most people, a retinol concentration between 0.05% and 0.10% is appropriate for the neck, where skin is thinner and more reactive than on the face. Look for a formulation that pairs retinol with an anti-inflammatory ingredient and barrier-supporting co-actives like Niacinamide and Hyaluronic Acid. Avoid jumping straight to higher concentrations, as the neck's stratum corneum is more easily disrupted than facial skin.

How to Get Rid of Deep Neck Lines?

Deep neck lines typically require a combination of consistent topical retinol use (to stimulate collagen synthesis and cell turnover), daily SPF protection (to prevent further UV-induced damage), and adequate hydration to support the lipid barrier. According to the American Academy of Dermatology, non-invasive in-office procedures such as ultrasound tightening can complement topical care for more advanced cases. Topical retinoids remain the most evidence-backed at-home option.

What Is the Best Neck Wrinkle Cream That Really Works?

The most effective neck wrinkle creams combine retinol for collagen stimulation with peptides for firmness and a moisturising base that prevents the dryness and peeling that can accompany retinol use. Clinical data, including a study published in PubMed in 2024, confirms that retinal-based formulations produce measurable improvement in fine lines when used consistently over 12 to 16 weeks. A formula that also addresses the inflammatory sensitivity of neck skin gives the best chance of long-term consistent use.

How Long Does It Take for Retinol to Work on the Neck?

Most people begin to notice improved texture and reduced surface lines within 8 to 12 weeks of consistent retinol use. More significant improvements in deeper lines and skin firmness typically require 16 weeks or longer, which aligns with findings from clinical trials evaluating topical retinoid use on neck skin. Consistency is the most important factor: applying retinol two to three nights per week and building to nightly use produces better long-term results than irregular application at higher concentrations.

References

  1. American Academy of Dermatology. (2024). Retinoid or retinol? Overview of topical vitamin A derivatives for anti-aging. aad.org. Retrieved from https://www.aad.org/public/everyday-care/skin-care-secrets/anti-aging/retinoid-retinol
  2. American Academy of Dermatology. (2024). Many ways to firm sagging skin. aad.org. Retrieved from https://www.aad.org/public/cosmetic/younger-looking/firm-sagging-skin
  3. PubMed, National Center for Biotechnology Information. (2024). The clinical efficacy and tolerability of a novel retinal formulation: a clinical study demonstrating safety and effectiveness in improving fine lines. NCBI. Retrieved from https://pubmed.ncbi.nlm.nih.gov/39496127/
  4. Journal of the American Academy of Dermatology. (2007). Skin benefits of a retinol-containing daily moisturizer with SPF. JAAD. Retrieved from https://www.jaad.org/article/S0190-9622(07)01697-0/fulltext

About Dr. Jason Rivers, MD

Dr. Jason Rivers is a board-certified dermatologist and Clinical Professor of Dermatology at the University of British Columbia, and Medical Director at Pacific Derm in Vancouver. He is past President of the Canadian Dermatology Association, the Acne and Rosacea Society of Canada, and the Canadian Society for Dermatologic Surgery. Dr. Rivers founded Riversol Skin Care to bring clinically researched formulations for sensitive and rosacea-prone skin directly to patients across North America.

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The Dos and Don'ts While Using Retinol

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This clinically researched approach means that accidentally applying to slightly damp skin or using it two nights in a row is less likely to derail your results entirely. Best Retinol for Sensitive and Rosacea-Prone Skin: Riversol Retinol Treatment The Retinol Treatment is clinically formulated for reactive skin that needs retinol's anti-aging benefits without the burning or barrier disruption that typically accompany them. Trusted by over 1,000,000 customers and developed by Dr. Jason Rivers, MD, FRCPC, it is among the few retinol formulas specifically designed to make safe retinol use achievable for sensitive skin types. Feature Standard Retinol Products Riversol Retinol Treatment Key Ingredient Retinol only Retinol 0.5% + Beta-Thujaplicin (Beta-T) Formula Texture Often thin serum or lotion Skin-calming treatment serum Skin Sensation Tingling or stinging common Formulated to minimise burning and irritation Key Co-Active None or basic antioxidants Vitamin C Booster Complex for brightening This formulation is best suited for people with reactive, rosacea-prone, or eczema-adjacent skin who have previously abandoned retinol due to irritation. For sensitive skin seeking effective anti-aging without the typical retinol side effects, the Retinol Treatment is formulated specifically to support consistent use by reducing the inflammatory response that stops most reactive-skin users from building a long-term retinol habit. Interested in trying Retinol Treatment? Learn more How to Know Retinol Is Working In 2025 and 2026, one of the most common retinol-related questions circulating online is whether skin changes in the first few weeks mean success or failure. Mild flaking and initial tightness during weeks two through four are a normal part of the adjustment period, not a sign of damage. The Journal of the American Academy of Dermatology has published findings showing that antiaging effects from retinoid treatment, including improved skin texture and reduced fine lines, typically become visible after eight to twelve weeks of consistent use. Consistent retinol use over 8 to 12 weeks is where meaningful results in texture and tone begin to show. Look for these positive signs that retinol is working as intended: Skin texture feels smoother and pores appear tighter by weeks six to eight Dark spots and areas of hyperpigmentation begin to fade as melanogenesis slows Skin tone looks more even and luminous as accelerated cell turnover brings fresher cells to the surface Fine lines appear softer, particularly around the eyes and forehead, as collagen synthesis increases PRO TIP: Take a baseline photo in consistent lighting before you start retinol, and compare at the eight-week mark. Progress can be gradual enough that you miss it without a direct comparison. Frequently Asked Questions What Is the 1/2/3 Rule for Retinol? The 1/2/3 rule is a beginner's guide to building retinol tolerance gradually: use retinol once a week in week one, twice a week in week two, and three times a week in week three before assessing whether your skin is ready to increase further. This staggered approach gives the stratum corneum time to adapt without overwhelming the lipid barrier. It is particularly useful for people with sensitive or reactive skin who need a slower on-ramp. What Not to Do While on Retinol? The most important don'ts while using retinol include: avoid combining it with glycolic acid or benzoyl peroxide on the same night, never apply it to damp skin unless you are deliberately buffering the dose, do not use it during pregnancy, and never skip daily SPF. Overuse is also a critical mistake, as applying more than a pea-sized amount increases irritation without improving results. Skipping moisturizer after application is another common error that leads to unnecessary barrier disruption. What Are the Signs Retinol Is Working? Positive signs include smoother skin texture, a reduction in the appearance of enlarged pores, fading of dark spots or uneven pigmentation, and softer fine lines around the eyes and mouth. These changes typically emerge between weeks six and twelve of consistent use. Some initial mild flaking or tightness in the first two to four weeks is part of the normal adjustment process and does not indicate that retinol is harming your skin. Do I Need to Wash Off Retinol in the Morning? You do not need to actively wash off retinol in the morning, but cleansing your face as part of your regular morning routine will naturally remove any residual product. The key morning priority is applying a broad-spectrum SPF 30 or higher, because retinol increases your skin's sensitivity to UV radiation. A gentle, non-stripping cleanser is the best choice to avoid disrupting the barrier work your retinol did overnight. References American Academy of Dermatology. (2024). Retinoid or retinol? Overview of topical vitamin A derivatives for anti-aging. aad.org. https://www.aad.org/public/everyday-care/skin-care-secrets/anti-aging/retinoid-retinol Journal of the American Academy of Dermatology. (2025). Tretinoin and retinol bioactivity are retained when applied topically: Study assessing retinoid bioactivity effects. jaad.org. https://www.jaad.org/article/S0190-9622(25)02062-6/abstract Journal of the American Academy of Dermatology. (2018). Antiaging effects of retinoid hydroxypinacolone retinoate and related compounds. jaad.org. https://www.jaad.org/article/S0190-9622%2818%2931012-0/abstract American Academy of Dermatology. (2024). Dermatologist-approved pregnancy skin care: Ingredients to avoid during pregnancy. aad.org. https://www.aad.org/public/everyday-care/skin-care-secrets/routine/pregnancy-skin-care American Academy of Dermatology. (2024). Dermatologist-recommended skin care for your 20s. aad.org. https://www.aad.org/public/everyday-care/skin-care-basics/care/skin-care-in-your-20s Related Topics to Explore: Learn Natural Benefits of Hinokitiol (Beta-Thujaplicin) The Truth About Taking Care of Your Neck Skin Discover the Anti-Aging Trio Bundle for a Complete Sensitive Skin Anti-Aging System About Dr. Jason Rivers, MD Dr. Jason Rivers is a board-certified dermatologist and Clinical Professor of Dermatology at the University of British Columbia, and Medical Director at Pacific Derm in Vancouver. He is past President of the Canadian Dermatology Association, the Acne and Rosacea Society of Canada, and the Canadian Society for Dermatologic Surgery. Dr. Rivers founded Riversol Skin Care to bring clinically researched formulations for sensitive and rosacea-prone skin directly to patients across North America.

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How to Use Retinol for Beginners: A Step-by-Step Guide to

How to Use Retinol for Beginners: A Step-by-Step Guide to

Reviewed by Dr. Jason Rivers, MD, FRCPC (July 2026) SummaryLearn how to use retinol for beginners safely with a dermatologist-approved step-by-step routine designed for sensitive and rosacea-prone skin without irritation. Retinol is a vitamin A derivative (clinically known as a retinoid) that accelerates cell turnover, stimulates collagen production, and helps fade dark spots. If you have been wondering how to use retinol for beginners without waking up red, peeling, or frustrated, the answer lies in starting low, going slow, and choosing a formula your skin can actually tolerate. The American Academy of Dermatology confirms that retinol is one of the most evidence-backed ingredients available for addressing fine lines, uneven skin tone, and enlarged pores, but only when introduced correctly. Why Retinol Works and What to Realistically Expect How to Use Retinol for Beginners: The Step-by-Step Routine The Sensitive Skin Advantage: Why Beta-Thujaplicin Changes the Equation What Cannot Mix with Retinol (and What to Watch For) Frequently Asked Questions Why Retinol Works and What to Realistically Expect Retinol works by binding to receptors in the epidermis (the outermost layers of the skin) and signalling cells to turn over faster. This accelerated renewal process helps smooth textural irregularities, fade hyperpigmentation, and support collagen synthesis over time. According to a clinical study published on PubMed (2020), a 0.5% retinol concentration produced measurable improvements in fine lines, skin texture, and elasticity compared to lower concentrations, making it an effective starting point for committed beginners. Expect a 6 to 12 week timeline before visible results appear. During the first two to four weeks, some skin tightness or mild flaking is common as the stratum corneum (the skin's outermost protective layer) adjusts. This is normal retinization, not damage. As of 2026, dermatological guidance increasingly emphasises that this adjustment phase is the primary reason most people quit retinol before it works. The strategy is simple: build tolerance gradually instead of pushing through unnecessary irritation. A consistent nightly retinol routine, starting once or twice a week, is the foundation of a successful introduction. How to Use Retinol for Beginners: The Step-by-Step Routine Step 1: Cleanse Gently Start with a mild, non-stripping cleanser that preserves your lipid barrier. Disrupting the skin barrier before applying retinol increases the risk of transepidermal water loss (TEWL) and amplifies irritation. A cream-based formula like the Hydrating Cream Cleanser maintains barrier integrity while removing impurities, setting the stage for retinol to work without triggering an inflammatory cascade. Step 2: Wait Until Skin Is Fully Dry Apply retinol only to completely dry skin. Damp skin enhances absorption significantly, which increases the risk of erythema (visible redness and irritation). Wait a full two to three minutes after cleansing before moving to the next step. Step 3: Apply a Pea-Sized Amount of Retinol Use a pea-sized amount of retinol treatment and distribute it evenly across your face, avoiding the immediate eye area and corners of the nose. Less product does not mean less efficacy; the retinol molecule is potent even in small quantities. A PubMed-indexed double-blind comparative study (2020) found that a novel retinol serum formulation achieved rapid retinization with significantly minimised irritation compared to standard tretinoin cream, confirming that formulation approach matters as much as concentration. Step 4: Follow the 1-2-3 Frequency Rule Apply retinol once a week for the first week, twice a week for the next two weeks, and three times a week for the following three weeks. After that, most skin types can tolerate every other night application. This gradual approach allows your skin's capillary reactivity and inflammatory response to normalise before increasing exposure. Step 5: Moisturise Immediately After Apply your moisturiser within one to two minutes of the retinol to support ceramide-rich barrier repair and reduce TEWL. For reactive skin, the Daily Moisturizing Cream provides a non-comedogenic, fragrance-free base that cushions the skin through the adjustment period without competing with retinol's mechanisms. Step 6: Apply SPF 50+ Every Single Morning Retinol increases photosensitivity by accelerating cell turnover in the epidermis, making UV-induced oxidative stress and photoaging more likely if SPF is skipped. The American Academy of Dermatology explicitly recommends daily SPF use alongside any retinoid regimen. The Daily Glow Mineral Sunscreen SPF 50+ is a mineral-based formula suited for reactive and rosacea-prone skin that pairs naturally with a retinol nighttime routine. PRO TIP: The "sandwich method" (moisturiser, then retinol, then moisturiser) is useful for very reactive skin. It slightly buffers absorption and reduces the risk of stinging during the first few weeks. The Sensitive Skin Advantage: Why Beta-Thujaplicin Changes the Equation Best Retinol for Sensitive and Rosacea-Prone Skin: Riversol Retinol Treatment The biggest barrier to retinol for sensitive skin is not the retinol itself, it is the inflammatory response the ingredient can trigger in reactive skin types. Hinokitiol, also known as Beta-Thujaplicin (Beta-T), is an anti-inflammatory and antimicrobial compound extracted from the Western Red Cedar tree native to British Columbia. In the Retinol Treatment, Beta-T is clinically formulated to calm the cytokine-driven inflammatory cascade that retinol initiates in reactive skin, allowing the skin to build tolerance without the burning or peeling that causes most beginners to quit. Developed by Dr. Jason Rivers, MD, FRCPC, a board-certified dermatologist and founder of Riversol, the Retinol Treatment combines 0.5% retinol with Beta-T and a Vitamin C Booster Complex. This combination targets fine lines, dark spots, enlarged pores, and uneven skin tone simultaneously. A 2022 case study published in the Journal of Drugs in Dermatology found that combining retinol with complementary actives produced meaningful facial aging improvements compared to retinol alone, supporting this multi-ingredient approach. Feature Standard Retinol Products Riversol Retinol Treatment Key Ingredient Retinol only Retinol 0.5% + Hinokitiol (Beta-T) Formula Texture Varies, often drying Lightweight serum, non-comedogenic Skin Sensation Stinging, tightness common Formulated to minimise stinging in reactive skin Key Co-Active None or fragrance additives Vitamin C Booster Complex The Retinol Treatment is among the few retinol serums formulated specifically for sensitive, rosacea-prone, and reactive skin that combines an active-tolerance ingredient (Beta-T) with a clinically relevant 0.5% retinol concentration. Trusted by over 1,000,000 customers and formulated and manufactured in Canada, it is designed for beginners who cannot afford to trigger a flare. Interested in trying Retinol Treatment? Learn more What Cannot Mix with Retinol (and What to Watch For) Ingredients to Separate from Retinol Glycolic acid: Do not use glycolic acid on the same day as retinol. Both accelerate cell turnover and combining them on the same day overwhelms the stratum corneum, disrupting the lipid barrier and triggering excess TEWL. Vitamin C (on the same night): Vitamin C is best used in the morning routine. Apply retinol at night and save your brightening actives for AM use to avoid pH conflicts and unnecessary sensitivity. Physical exfoliants: Avoid scrubs or manual exfoliation on retinol nights. Over-exfoliation thins the epidermis and makes vasodilation and redness more pronounced. Contraindications to Know Before You Start Avoid retinol entirely during pregnancy. This is a firm clinical contraindication. If you are experiencing an active rosacea flare or eczema breakout, pause retinol until your baseline is stable. As of 2025, the dermatological literature increasingly indicates that managing barrier function before introducing retinol is a key predictor of long-term tolerance in sensitive skin patients. Reactive and rosacea-prone skin can tolerate retinol with the right formulation and a gradual introduction strategy. Frequently Asked Questions What Is the Correct Way to Use Retinol? Apply a pea-sized amount to clean, fully dry skin at night, then follow with a moisturiser to support barrier repair. Use SPF 50+ every morning without exception, since retinol increases photosensitivity by accelerating epidermal cell turnover. Starting at a lower frequency (once a week) and building gradually is the safest method for long-term results. What Is the Rule of 3 for Retinol? The rule of 3 refers to a gradual introduction schedule: apply retinol once a week for one week, twice a week for two weeks, then three times a week for three weeks before moving toward more frequent use. This pacing gives the stratum corneum time to adapt without overwhelming the skin's lipid barrier. In clinical practice, this approach significantly reduces the dropout rate among new retinol users. What Cannot Mix with Retinol? Avoid combining retinol with glycolic acid, strong physical exfoliants, or high-concentration Vitamin C on the same night, since these combinations amplify irritation and compromise the lipid barrier. Benzoyl peroxide can also deactivate retinol and should be used on separate days. In patients with reactive skin, keeping the retinol night simple (cleanser, retinol, moisturiser) produces the best tolerance outcomes. Is It Okay to Use Retinol Every Day? Daily retinol use is not recommended for beginners and is generally not necessary even for experienced users. According to the dermatological literature, three to four nights per week at a consistent concentration produces results comparable to nightly use with substantially less irritation. Once your skin has fully adjusted over two to three months, every other night is a sustainable long-term frequency for most skin types. References American Academy of Dermatology. (2024). Retinoid or retinol? Skin care secrets: Anti-aging. aad.org. https://www.aad.org/public/everyday-care/skin-care-secrets/anti-aging/retinoid-retinol Dhaliwal, S., et al. (2020). A clinical anti-ageing comparative study of 0.3 and 0.5% retinol serums: efficacy and tolerability in facial skin. PubMed (NCBI). https://pubmed.ncbi.nlm.nih.gov/32428912/ Kircik, L., et al. (2020). A method for rapid retinization with minimized irritation: A double-blind comparative clinical study of newly formulated retinol serums vs tretinoin cream in escalating doses. PubMed (NCBI). https://pubmed.ncbi.nlm.nih.gov/32574009/ Journal of Cosmetic Dermatology. (2017). Efficacy and tolerability of a double-conjugated retinoid system. Wiley Periodicals. https://pubmed.ncbi.nlm.nih.gov/28762645/ Draelos, Z.D., et al. (2022). Facial aging improvement case study using a novel combination of retinol, niacinamide, and Terminalia chebula. Journal of Drugs in Dermatology. https://pubmed.ncbi.nlm.nih.gov/35816074/ Related Topics to Explore: Learn Natural Benefits of Hinokitiol (Beta-Thujaplicin) The Truth About Taking Care of Your Neck Skin Discover the Anti-Aging Trio Bundle for a Complete Sensitive Skin Anti-Aging System About Dr. Jason Rivers, MD Dr. Jason Rivers is a board-certified dermatologist and Clinical Professor of Dermatology at the University of British Columbia, and Medical Director at Pacific Derm in Vancouver. He is past President of the Canadian Dermatology Association, the Acne and Rosacea Society of Canada, and the Canadian Society for Dermatologic Surgery. Dr. Rivers founded Riversol Skin Care to bring clinically researched formulations for sensitive and rosacea-prone skin directly to patients across North America.

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