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Why a dermatologist chose Hinokitiol

Why a dermatologist chose Hinokitiol

“The more research I did, the more impressed I was with this unique ingredient and its ability to reduce the look of sunspots and improve skin clarity and texture.”

Dr. Jason Rivers

Dermatologist + Founder of Riversol

Discover The Riversol Story

One ingredient
Multiple benefits

Hinokitiol’s properties make it relevant to several of the concerns sensitive skin brings to a dermatologist’s office.

Powerful antioxidant

Helps defend against oxidative stress.

Helps calm skin

Supports calmer-looking skin and visible redness concerns.

Targets uneven pigmentation

Relevant to the pathway involved in excess melanin production.

Naturally antimicrobial

Demonstrates antimicrobial activity in published laboratory research.

From the forests of the Pacific Northwest

From the forests of the Pacific Northwest

Hinokitiol, also known as beta-thujaplicin, occurs naturally in select trees in the cypress family, including Pacific red cedar.

01

Forest

Pacific red cedar (Thuja plicata), an iconic species native to the Pacific Northwest.

02

Heartwood

Hinokitiol occurs among the natural compounds found in the tree’s heartwood.

03

Molecule

Beta-thujaplicin, also known as Hinokitiol.

How Hinokitiol works

What published laboratory research has found.

Antioxidant activity

Helps counter oxidative processes associated with environmental stress.

Anti-inflammatory activity

Published research has investigated effects on inflammatory signalling.

Tyrosinase / pigmentation

Research has shown inhibition of tyrosinase activity and melanin biosynthesis.

See the research

Zhu YJ et al. (2010), J Enzyme Inhib Med Chem. · Choi YG et al. (2006), J Dermatol Sci.

Antimicrobial activity

Hinokitiol has demonstrated antimicrobial activity in laboratory research.

More than a skincare story

It’s a molecule scientists keep studying.

Pigmentation

Tyrosinase + melanin biosynthesis

Inflammation

Inflammatory signalling

Antimicrobial activity

Laboratory antimicrobial research

Oxidative stress

Antioxidant activity

View the research

01

Preventive effects of beta-thujaplicin against UVB-induced MMP-1 and MMP-3 mRNA expressions in skin fibroblasts.

Cherng JY, Chen LY, Shih MF (2012). Am J Chin Med. 40(2):387–98.

View abstract

02

Differential regulation of melanosomal proteins after hinokitiol treatment.

Choi YG, Bae EJ, Kim DS, Park SH, Kwon SB, Na JI, Park KC (2006). J Dermatol Sci. 43(3):181–8.

View abstract

03

Inhibitory effects of hinokitiol on tyrosinase activity and melanin biosynthesis and its antimicrobial activities.

Zhu YJ, Qiu L, Zhou JJ, Guo HY, Hu YH, Li ZC, Wang Q, Chen QX, Liu B (2010). J Enzyme Inhib Med Chem. 25(6):798–803.

View abstract

Finding Hinokitiol wasn’t the hard part||Formulating with it was

Finding Hinokitiol wasn’t the hard part
Formulating with it was

Hinokitiol can be challenging to formulate into topical skincare. Riversol spent years developing formulations that could successfully incorporate this unusual ingredient into skincare designed for sensitive skin.

  • Rare ingredient
  • Difficult chemistry
  • Years of formulation expertise

That’s why Hinokitiol became a signature of Riversol.

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